SMIM3 — Small integral membrane protein 3
SMIM3 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SMIM3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | IL-1 Receptor Signaling Inflammatory | CHIC2, GNAI1, IL1R1, MMD, PDLIM1, PRR16, ST3GAL1, TUSC3 | View in SCUBA |
| Gamma-delta T cells | Hypoxia Tissue Adaptation Tissue residence | ABCB1, ADAMTS17, ANKRD28, CCRL2, EPAS1, FAM3C, KLHL6, LDLRAD4 +10 more | |
| Innate lymphoid cells | Inflammasome Activation Inflammation | ANKRD28, AP3D1, ARHGEF7, CCNH, CD55, CDC42SE1, CHD7, CHKA +19 more | View in SCUBA |
| Macrophages | NRF2 Oxidative Stress Stress | ACOT9, AHRR, ARMC9, BASP1, CARD19, CCDC71L, CD226, CLDND1 +27 more | View in SCUBA |
| Monocytes | Innate Immune Transcription Innate immunity | CARD19, COG3, CSNK1E, ELF4, EXTL3, PCIF1, RBM38, ZFYVE9 | View in SCUBA |
| Natural Killer cells | Gut-Homing NK Gut residency | CCR9, FAM3C, GRAMD2B, OXNAD1, PLPP1, PRKAR2B, SNX9, TRAT1 | View in SCUBA |
About the gene
| Synonyms | C5orf62, MSTP150, NID67 |
|---|---|
| Chromosome | 5: 150778757-150796734 |
| Predicted location | Membrane |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted membrane proteins |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.