SCUBA

MICOS10 — Mitochondrial contact site and cristae organizing system subunit 10

MICOS10 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

MICOS10's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsATP Synthase Complex
Mitochondrial & OxPhos
ATP5F1D, ATP5F1E, ATP5MC2, ATP5MC3, ATP5MF, ATP5MG, ATP5MK, ATP5PD +23 more
Innate lymphoid cellsMitochondrial Organization
Mitochondrial & OxPhos
ARL5A, ATP5MJ, ATP5MK, BBLN, C18orf32, CIAO2B, CYRIB, EEF1G +21 moreView in SCUBA
Lymphatic endothelialMitochondrial Cristae Organization
Mitochondrial & OxPhos
ATP5MJ, ATP6V0C, BEX4, EEF1G, EIF4A1, KRTCAP2, MICOS13, MIF +6 moreView in SCUBA
MacrophagesOxidative Phosphorylation
Mitochondrial & OxPhos
ATP5F1C, ATP5MC3, ATP5PD, ATP5PO, COX5B, COX6C, LAMTOR2, MICOS13 +7 moreView in SCUBA
Mucosal-associated invariant T cellT cell Identity
T cell maturation
ARPC1B, BLOC1S1, C4orf3, CD3D, CHKB, CPNE1, DDX39B, HMGN3 +9 more
Natural Killer cellsMitochondrial Membrane Organization
Mitochondrial & OxPhos
ATP5MJ, ATP5MK, BBLN, CIAO2B, GABARAP, H3-3A, PHB1, SEPTIN7 +1 moreView in SCUBA
Smooth muscle cellsHistone Variant Chromatin
DNA/chromatin regulation
ATP5MJ, ATP5MK, ECRG4, H2AZ1, H2AZ2, H3-3A, H3-3B, MACROH2A1 +6 moreView in SCUBA

About the gene

SynonymsC1orf151, FLJ36999, Mic10, MINOS1, MIO10, RP5-1056L3.2
Chromosome1: 19484403-19629821
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classPredicted intracellular proteins, Predicted membrane proteins, Transporters

Function

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.