NDUFB6 — NADH:ubiquinone oxidoreductase subunit B6
NDUFB6 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NDUFB6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Mitochondrial Translation Mitochondrial & OxPhos | ARF5, CBX6, CCDC124, CISD3, DCTN2, DDA1, EIF4E2, FKBP3 +17 more | View in SCUBA |
| Gamma-delta T cells | Mitochondrial ETC Mitochondrial & OxPhos | COX7B, HMGB1, HMGN1, HMGXB4, LSM5, PSMA6, RANGRF, RBM17 +5 more | |
| Hematopoietic progenitor cells | Proteostasis & OxPhos Mitochondrial & OxPhos | COX5A, EIF5A, HNRNPF, HSPA8, ILF2, MRPS34, PSMB5, SLBP | |
| Innate lymphoid cells | Oxidative Phosphorylation Mitochondrial & OxPhos | APEX1, ATP5F1A, CCNC, COA3, DMAC1, ESD, HDAC2, HINT2 +15 more | View in SCUBA |
| Macrophages | Glycolytic Metabolism Housekeeping | ARL1, ARPC5, ATP5PB, ATRAID, C4orf3, CALM1, CAPZA2, CHMP5 +30 more | View in SCUBA |
About the gene
| Synonyms | B17, CI |
|---|---|
| Chromosome | 9: 32553001-32573184 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Electron transport, Respiratory chain, Transport |
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.