PLXDC1 — Plexin domain containing 1
PLXDC1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLXDC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Homeostatic Stromal Identity ECM production | ADAMTSL1, ADAMTSL3, EPB41L2, KAZALD1, LRIG1, NFIB, NUPR1, PDE5A +4 more | View in SCUBA |
| Gamma-delta T cells | Redox Stress Response Stress | BEX2, BEX4, CITED4, EEF1A1, FMNL3, FTL, GRINA, LTBP3 +5 more | |
| Macrophages | Resident Mac Identity Tissue homeostasis | ACVRL1, CCND1, CD200R1, CFD, CR1, CTSF, EMB, EPHX1 +16 more | View in SCUBA |
| Pericytes | Pericyte Identity Signaling Developmental | ADCY3, CCDC102B, FBLIM1, NOTCH3, OLFML2B, PDGFRB, PEAK1 | View in SCUBA |
About the gene
| Synonyms | TEM3, TEM7 |
|---|---|
| Chromosome | 17: 39063313-39154394 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Plays a critical role in endothelial cell capillary morphogenesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.