PPP1R2 — Protein phosphatase 1 regulatory inhibitor subunit 2
PPP1R2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPP1R2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Chromatin Modification DNA/chromatin regulation | AKAP13, CREBRF, EPC1, GCC2, GPBP1, JMJD1C, KMT2E, OFD1 +6 more | View in SCUBA |
| CD4⁺ T cells | Transcription/RNA processing RNA processing | ANKRD17, BDP1, CCDC97, CDK13, CHIC2, CLK4, CNOT6L, CRNKL1 +29 more | View in SCUBA |
| Gamma-delta T cells | AHR/NF-κB Survival Immune regulation | ABCC1, AHR, ANKRD37, AREG, BAIAP2, BCL2L11, BEND4, BIRC3 +24 more | |
| Innate lymphoid cells | Lymphocyte Apoptosis Regulation Immune regulation | ANP32B, ARMCX3, CCDC69, CHD2, DHRS7, ELF1, FXYD5, GLIPR1 +14 more | View in SCUBA |
| Macrophages | RNA Splicing Regulation Housekeeping | ABCF1, CDC42SE1, CDC5L, CDV3, CEBPZ, DNAJC7, DYNC1LI1, FGFR1OP2 +13 more | View in SCUBA |
About the gene
| Synonyms | IPP2, PPP1R2A |
|---|---|
| Chromosome | 3: 195514428-195543386 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | Protein phosphatase inhibitor |
| Biological process | Carbohydrate metabolism, Glycogen metabolism |
Function
Inhibitor of protein-phosphatase 1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.