RASA2 — RAS p21 protein activator 2
RASA2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RASA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA Splicing Factors RNA processing | ARGLU1, CDKN2D, CLK1, ERO1B, FUS, GLS, HNRNPA2B1, ID1 +8 more | View in SCUBA |
| Gamma-delta T cells | mRNA Splicing Regulation RNA processing & translation | ARF6, BTG3, CAPN7, CDV3, CELF2, CNBD2, CUL3, CYTIP +18 more | |
| Innate lymphoid cells | NK/ILC1 Identity Differentiation | ABCA5, ARHGAP15, CD37, CD96, CD99, CTSD, EPC1, GIMAP2 +17 more | View in SCUBA |
| Macrophages | Endosomal Vesicle Trafficking Vesicular traficking | ADAM17, AP3B1, ARFGEF1, ARID1B, ARK2N, ASAP1, ATF6, ATP11A +48 more | View in SCUBA |
| Mucosal-associated invariant T cell | Cytoskeletal Migration migration & adhesion | CHST11, HDAC9, MGAT5, NCAM1, NCOA2, PITPNC1, SSH2 |
About the gene
| Synonyms | GAP1M |
|---|---|
| Chromosome | 3: 141487027-141615344 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, RAS pathway related proteins |
| Molecular function | GTPase activation |
Function
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.