SLC25A25 — Solute carrier family 25 member 25
SLC25A25 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC25A25's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | NF-κB Early Response Inflammation | BCL3, BHLHE40, ICAM1, INSIG1, ITPKC, KLF10, LDLR, MYADM +3 more | View in SCUBA |
| Fibroblasts | Proteotoxic Stress Survival Stress | ARL5B, BAG3, DNAJA4, ICAM1, PPIF, PPP1R15B, TIPARP, TNFRSF10D | View in SCUBA |
| Smooth muscle cells | Chaperonin heat-shock Stress | CYCS, DUSP1, HSPD1, HSPE1, ODC1, PABPC1, SRSF3, UBE2D3 | View in SCUBA |
About the gene
| Synonyms | KIAA1896, MCSC, PCSCL |
|---|---|
| Chromosome | 9: 128068201-128109245 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Antiport, Transport |
Function
Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.