SLC25A39 — Solute carrier family 25 member 39
SLC25A39 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC25A39's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Mitochondrial OxPhos Mitochondrial & OxPhos | ADSL, AP1S1, CD151, COMTD1, COX5A, DDT, DNPH1, DUSP23 +20 more | |
| Goblet cells | Mitochondrial Biogenesis Mitochondrial & OxPhos | ARPC5L, CALM1, EIF5A, LSM7, MRPL17, MRPL20, MRPL41, PFN1 +4 more | View in SCUBA |
| Innate lymphoid cells | ILC1 Cytoskeletal Metabolic Cytoskeleton & motility | ATP5F1B, ATXN10, CCT7, CD82, DNPH1, GADD45GIP1, HMGA1, MEA1 +14 more | View in SCUBA |
| Macrophages | Macrophage Proliferation Cell cycle | ALDH16A1, ARL6IP4, BIN2, BRI3BP, CCDC112, CCP110, CD33, CD36 +15 more | View in SCUBA |
About the gene
| Synonyms | CGI-69, FLJ22407 |
|---|---|
| Chromosome | 17: 44319625-44324870 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Heme biosynthesis, Transport |
Function
Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron- sulfur clusters, as well as erythropoiesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.