ZZEF1 — Zinc finger ZZ-type and EF-hand domain containing 1
ZZEF1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZZEF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Mature colonocyte brush-border Epithelial development | AGMO, ATP8A1, CA3, CNKSR3, COBL, EMB, EPB41L3, NGEF +2 more | View in SCUBA |
| Gamma-delta T cells | Transcription-RNA Coupling DNA/chromatin regulation | AKNA, AP1G1, BTAF1, BZW1, CRNKL1, DDX6, DNTTIP2, DYNC1H1 +26 more | |
| Macrophages | Chromatin Epigenetic Regulation Housekeeping | ABHD17B, ANKH, ARHGAP21, CCNH, CTTNBP2NL, DMXL1, EEIG2, ELF2 +21 more | View in SCUBA |
| Mucosal-associated invariant T cell | Nuclear-Cytoskeletal Organization Housekeeping | DDB1, GANAB, HYOU1, IPO7, MYH9, NOLC1, NUMA1, PRPF8 +4 more |
About the gene
| Synonyms | FLJ10821, KIAA0399, ZZZ4 |
|---|---|
| Chromosome | 17: 4004445-4143030 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Molecular function | Activator |
| Biological process | Transcription, Transcription regulation |
Function
Histone H3 reader which may act as a transcriptional coactivator for KLF6 and KLF9 transcription factors
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.