SCUBA

NDUFS7 — NADH:ubiquinone oxidoreductase core subunit S7

NDUFS7 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFS7's module in each cell type

Cell typeModuleShares the module with
CD8⁺ T cellsRNA Splicing Complex
RNA processing & translation
ATP6V0B, ATP6V1F, EIF3I, MRPS6, PARK7, PRDX6, PSMD4, SF3B5 +3 moreView in SCUBA
EndothelialActomyosin Contractility
Cytoskeletal
BCL7C, BLCAP, C20orf204, CMBL, CTDSPL, DDB2, FLRT2, ITM2C +11 moreView in SCUBA
Gamma-delta T cellsComplex I Assembly
Mitochondrial & OxPhos
AKR7A2, AP2S1, BLOC1S1, DCTN2, HSD17B10, LAMTOR2, MGMT, MRPL34 +13 more
Goblet cellsElectron Transport Chain
Mitochondrial & OxPhos
ATP5IF1, ATP5ME, COX5B, DCXR, NDUFA2, NDUFA3, NDUFB1, NDUFB10 +5 moreView in SCUBA
Innate lymphoid cellsProteasome & COPI Trafficking
Protein processing & ER
CCT8, COPE, COPZ1, COX5A, FIBP, GPX4, LAMTOR4, MDH1 +5 moreView in SCUBA
Lymphatic endothelialOxidative Phosphorylation
Mitochondrial & OxPhos
ATP5F1C, ATP5IF1, ATP5MC1, ATP5MC3, ATP5MF, ATP5PD, ATP5PF, ATP5PO +5 moreView in SCUBA
MacrophagesComplex I / NADH Dehydrogenase
Mitochondrial & OxPhos
AHCY, ANP32A, ANTKMT, APEX1, ARL2, ATIC, ATP5F1A, ATP5ME +31 moreView in SCUBA
Mucosal-associated invariant T cellMitochondrial Metabolism & Redox
Mitochondrial & OxPhos
ATP5PF, CHURC1, DAD1, DHRS7, EGLN2, HMOX2, ITM2B, MRPS21 +7 more

About the gene

SynonymsCI-20, FLJ45860, FLJ46880, PSST
Chromosome19: 1383527-1395589
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Molecular functionOxidoreductase, Translocase
Biological processElectron transport, Respiratory chain, Transport

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.