TAF15 — TATA-box binding protein associated factor 15
TAF15 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TAF15's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Chromatin Remodeling DNA/chromatin regulation | ACTN4, ANP32E, AP2B1, CCDC82, EIF2B1, EXOSC10, FAR1, FLII +17 more | |
| Goblet cells | hnRNP RNA Processing RNA processing & translation | CCT2, HNRNPAB, HNRNPD, HNRNPR, ILF3, IMPA2, SERBP1, SET | View in SCUBA |
| Innate lymphoid cells | Cell Cycle Regulation Cell cycle | CDKN1B, FLI1, GLG1, KIF2A, RAD21, TBRG1 | View in SCUBA |
| Macrophages | Transcriptional Regulation Housekeeping | AATF, ABHD5, ARID3B, DCP1A, GGNBP2, MIA2, MSI2, NR2C2 +18 more | View in SCUBA |
| Mucosal-associated invariant T cell | Nuclear-Cytoskeletal Organization Housekeeping | DDB1, GANAB, HYOU1, IPO7, MYH9, NOLC1, NUMA1, PRPF8 +4 more |
About the gene
| Synonyms | hTAFII68, Npl3, RBP56, TAF2N |
|---|---|
| Chromosome | 17: 35809482-35864615 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | DNA-binding, RNA-binding |
Function
RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Can enter the preinitiation complex together with the RNA polymerase II (Pol II)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.