SCUBA

RFLNB — Refilin B

RFLNB belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RFLNB's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsMetabolic reprogramming
Housekeeping
ATG16L2, ATP1A1, CCNYL1, CSKMT, EIF1AY, FAM241A, HMGCS1, ING1 +12 moreView in SCUBA
EndothelialBasement Membrane Assembly
ECM remodeling
COL15A1, COL4A1, COL4A2, HSPG2, KIFC3, MGAT4A, NDST1, NOL4L +4 moreView in SCUBA
EnterocytesLong-gene Nuclear Transcripts
Technical artifact
ADAMTSL1, KHDRBS2, LIN7A, OPCML, PAQR5, PIGZ, PLCL1, RALYL +3 moreView in SCUBA
FibroblastsWNT-modulating Fibroblast
Developmental
CIB2, COL4A5, DMKN, F3, FIP1L1, FRZB, GPSM3, HSD17B2 +9 moreView in SCUBA
Hematopoietic progenitor cellsErythroid Glycolysis
Erythropoietic
CMBL, ENO1, GAPDH, GYPC, LMO2, LY6E, MAP7, NENF +3 more
MacrophagesLow-Coherence Mixed
Technical artifact
AAMP, ALKBH7, CDC123, COMMD5, DNTTIP1, EIF3G, EIF4E2, FAM32A +8 moreView in SCUBA
MonocytesLeukotriene-Alarmin Response
Inflammatory
ALOX5AP, CDA, METTL9, MTARC1, PLBD1, QPCT, S100A12, TMEM38AView in SCUBA
PericytesBasement Membrane Maintenance
ECM production
CALCRL, DYSF, EXOC3L1, FAM167B, GRB10, HSPG2, PPM1F, RAPGEF4 +1 moreView in SCUBA

About the gene

SynonymsCfm1, FAM101B, MGC45871, RefilinB
Chromosome17: 439978-445939
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Function

Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in the formation of cartilaginous skeletal elements

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.