ITPRIP — Inositol 1,4,5-trisphosphate receptor interacting protein
ITPRIP belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ITPRIP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | BMP-ID Stress Response Stress | BHLHE40, CCDC184, CFAP20, FOXC2, GADD45G, GDF15, GDNF, HAS1 +9 more | View in SCUBA |
| Gamma-delta T cells | Circadian Clock DNA/chromatin regulation | BHLHE40, CDK17, CPEB2, CRY1, IRF1, MEF2D, NR1D2, PRKX +5 more | |
| Macrophages | Hypoxia-driven Activation Inflammatory | ACVR1B, ADAM10, ADAM9, ALCAM, ANO6, B3GNT2, BTG1, C5AR1 +33 more | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB Negative Feedback Immune regulation | ARL4A, BCAS2, CSRNP1, CXCR4, ENSG00000285976, IDS, NFKBIA, NFKBIB +7 more | |
| Natural Killer cells | Circadian Innate Signaling Inflammation | ARRDC2, CRY1, MGAT4A, NOCT, PTPRE, SLC15A4, TRAPPC10, UAP1 +1 more | View in SCUBA |
| Neutrophils | C5aR Complement Activation Innate immunity | ADGRG3, C5AR1, CD55, LAPTM5, MCL1, PFKFB3, PTPRE, RYBP +3 more |
About the gene
| Synonyms | bA127L20.2, DANGER, KIAA1754 |
|---|---|
| Chromosome | 10: 104309698-104338465 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.