FIBP — FGF1 intracellular binding protein
FIBP belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FIBP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | ER-Golgi Trafficking Protein processing & ER | BLOC1S1, CLIC1, COPE, COPZ1, IFI27L2, MYL6, RAP1B, SURF4 +1 more | View in SCUBA |
| Endothelial | ER-Golgi Trafficking Protein processing & ER | ARPC1A, CCT8, GDI2, GGCT, LMAN2, MAP2K2, MRPS16, PAICS +10 more | View in SCUBA |
| Gamma-delta T cells | Mitochondrial OxPhos Mitochondrial & OxPhos | ADSL, AP1S1, CD151, COMTD1, COX5A, DDT, DNPH1, DUSP23 +20 more | |
| Innate lymphoid cells | Proteasome & COPI Trafficking Protein processing & ER | CCT8, COPE, COPZ1, COX5A, GPX4, LAMTOR4, MDH1, NDUFC2 +5 more | View in SCUBA |
| Macrophages | Spliceosomal snRNP Cell cycle | ANAPC11, BANF1, CCDC25, CCT8, ERH, FKBP3, GLRX5, IER3IP1 +30 more | View in SCUBA |
About the gene
| Synonyms | FGFIBP |
|---|---|
| Chromosome | 11: 65883740-65888531 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
May be involved in mitogenic function of FGF1. May mediate with IER2 FGF-signaling in the establishment of laterality in the embryo (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.