ARPC1A — Actin related protein 2/3 complex subunit 1A
ARPC1A belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARPC1A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | ER-Golgi Trafficking Protein processing & ER | CCT8, FIBP, GDI2, GGCT, LMAN2, MAP2K2, MRPS16, PAICS +10 more | View in SCUBA |
| Goblet cells | ER Protein Processing Protein processing & ER | ALG5, ARPC3, COPZ1, DAD1, DYNLT1, POMP, PSMA5, SPCS1 | View in SCUBA |
| Pericytes | Actin Dynamics Cytoskeletal | CCND1, DSTN, EMP3, MGST3, NDUFA4, PTP4A3, S100A6 | View in SCUBA |
| Smooth muscle cells | Vascular SMC Identity Contractility | ADIRF, BCAM, CCDC3, CRIP1, EFHD1, GPRC5C, GPX3, HRC +10 more | View in SCUBA |
About the gene
| Synonyms | Arc40, SOP2Hs, SOP2L |
|---|---|
| Chromosome | 7: 99325898-99366262 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding |
Function
Probably functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.