SCUBA

IFI27L2 — Interferon alpha inducible protein 27 like 2

IFI27L2 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

IFI27L2's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsActin Cytoskeleton
Cytoskeletal
ARHGDIB, ARPC3, ATP5MG, CAPNS1, GMFG, OAZ1, SERF2, TAF10 +1 moreView in SCUBA
CD4⁺ T cellsInterferon-stimulated genes
Anti-viral
APOBEC3G, ARPC4, ARPC5L, BAK1, BST2, DCTN3, ECH1, ETFB +14 moreView in SCUBA
CD8⁺ T cellsER-Golgi Trafficking
Protein processing & ER
BLOC1S1, CLIC1, COPE, COPZ1, FIBP, MYL6, RAP1B, SURF4 +1 moreView in SCUBA
EndothelialMHC Class I Presentation
Inflammation
B2M, BST2, BTN3A1, BTN3A2, CYSTM1, HLA-A, HLA-B, HLA-C +1 moreView in SCUBA
Gamma-delta T cellsMitochondrial OxPhos
Mitochondrial & OxPhos
ADSL, AP1S1, CD151, COMTD1, COX5A, DDT, DNPH1, DUSP23 +20 more
Innate lymphoid cellsILC1 Inflammatory Activation
Inflammation
ALOX5AP, CNOT7, COMMD10, ELAVL1, FKBP8, FNTA, IL32, LPXN +11 moreView in SCUBA
MacrophagesOxidative Metabolic Program
Mitochondrial & OxPhos
ACADM, CA2, CALM3, CAPG, COQ2, CSRP1, CSTB, DENND2D +29 moreView in SCUBA
Natural Killer cellsGut-Homing NK Maturation
Gut residency
ANXA2, BIN1, DHRS7, HECA, ITGB7, KLF9, LGALS1, NDUFB7 +5 moreView in SCUBA

About the gene

SynonymsFAM14A, TLH29
Chromosome14: 94127779-94130253
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Biological processApoptosis

Function

Plays a role in the apoptotic process and has a pro-apoptotic activity

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.