HECA — Hdc homolog, cell cycle regulator
HECA belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HECA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | GIMAP survival Immune regulation | ABLIM1, AKT3, ANKRD13D, ARL4C, C16orf54, CA5B, COPA, CRBN +16 more | View in SCUBA |
| Gamma-delta T cells | mRNA Splicing Regulation RNA processing & translation | ARF6, BTG3, CAPN7, CDV3, CELF2, CNBD2, CUL3, CYTIP +18 more | |
| Innate lymphoid cells | ILC3 identity Differentiation | BHLHE40, BRD4, CASK, CITED2, GLUL, GNAS, IGFBP7, IQGAP1 +19 more | View in SCUBA |
| Mucosal-associated invariant T cell | MAIT Cell Identity T cell maturation | AFF3, DDX3Y, DKK3, DSE, EPAS1, FKBP5, FYN, GLIPR1 +16 more | |
| Natural Killer cells | Gut-Homing NK Maturation Gut residency | ANXA2, BIN1, DHRS7, IFI27L2, ITGB7, KLF9, LGALS1, NDUFB7 +5 more | View in SCUBA |
| Neutrophils | Neutrophil Survival FOXO-MK2 Developmental | ARIH1, FCAR, FGD4, FOXO3, IPMK, MAP3K2, MAPKAPK2, RAB8B +1 more |
About the gene
| Synonyms | dJ225E12.1, HDC, HDCL, hHDC |
|---|---|
| Chromosome | 6: 139135080-139180802 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Developmental protein |
Function
May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.