LAPTM4A — Lysosomal protein transmembrane 4 alpha
LAPTM4A belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LAPTM4A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cell cycle regulators DNA/chromatin regulation | CCDC28A, CCNDBP1, CFAP20, EAPP, IFNAR2, RBBP4, SH3GLB1 | View in SCUBA |
| Fibroblasts | Translation Initiation Housekeeping | CCNI, CD99, CNBP, EIF3E, EIF3F, ESD, HNRNPA1, ITM2B +3 more | View in SCUBA |
| Goblet cells | Epithelial Maintenance Housekeeping | COX7A2L, DDAH2, IP6K2, MARCKS, METTL9, MKRN1, RNF44 | View in SCUBA |
| Macrophages | Autophagy Lysosomal Regulation Lysosomal & pahgocytosis | ADIPOR1, ARL8A, ATOSB, BCL10, BROX, CCR1, CEBPB, CHMP2B +22 more | View in SCUBA |
| Smooth muscle cells | Ribonucleoprotein & translation RNA processing & translation | CRYAB, CYB5R3, EEF1B2, HMGB1, HNRNPC, MAGED2, NACA, NCL +5 more | View in SCUBA |
About the gene
| Synonyms | HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp |
|---|---|
| Chromosome | 2: 20032650-20051628 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | Transport |
Function
May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.