REEP3 — Receptor accessory protein 3
REEP3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
REEP3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | TGF-beta ECM Remodeling ECM remodeling | ADAM10, APLP2, CCNDBP1, CYB5R3, DHRS3, EFEMP2, GNAS, HIPK2 +10 more | View in SCUBA |
| Enterocytes | ER-autophagy homeostasis Protein processing & ER | AQP11, CCSER2, CTSD, MFSD2A, PLOD2, RB1CC1, RESF1, SMPDL3A +1 more | View in SCUBA |
| Fibroblasts | Actin-Integrin Adhesion Migration & adhesion | ACTR2, ACTR3, C5orf24, CAP1, CD151, DEGS1, FERMT2, GNB1 +5 more | View in SCUBA |
| Innate lymphoid cells | ILC1 Inflammatory Activation Inflammation | ABHD15, ALDOC, ARL2BP, C20orf204, CCL20, CPNE7, EIPR1, ERG28 +21 more | View in SCUBA |
About the gene
| Synonyms | C10orf74, Yip2b |
|---|---|
| Chromosome | 10: 63521401-63625128 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.