TGFBI — Transforming growth factor beta induced
TGFBI belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TGFBI's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | TGF-beta Fibrosis ECM production | ATP1B3, FKBP10, LOXL2, PLOD1, PMEPA1, SPTSSA, WNT5A | View in SCUBA |
| Goblet cells | Inflammatory Goblet Remodeling Stress | C2CD4A, CLCA1, COL16A1, FMOD, GALNT8, GPX2, IFITM2, KCNE3 +3 more | View in SCUBA |
| Pericytes | Inflammatory ECM Remodeling ECM remodeling | CCDC80, CD44, FHL2, FMO3, FN1, PDLIM3, RARRES2, TNC +1 more | View in SCUBA |
| Smooth muscle cells | Activated Myofibroblast Activation | CNN3, EPHX1, IFI16, IGFBP4, LAPTM4B, NNMT, SERPING1, SSR4 +3 more | View in SCUBA |
About the gene
| Synonyms | BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1 |
|---|---|
| Chromosome | 5: 136028988-136063818 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Biological process | Cell adhesion, Sensory transduction, Vision |
Function
Plays a role in cell adhesion. May play a role in cell-collagen interactions (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.