SCUBA

SSR4 — Signal sequence receptor subunit 4

SSR4 belongs to a gene co-expression module in 11 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SSR4's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsRibosome biogenesis
Housekeeping
APEX1, APRT, C1QBP, CCDC59, HNRNPA1, IMPDH2, LBH, LDHA +17 moreView in SCUBA
EnterocytesRedox Detoxification
Stress
CD9, CDX1, CYBA, GSTK1, GSTP1, KRT18, PYCARD, SEC61B +3 moreView in SCUBA
FibroblastsER Secretory Processing
Housekeeping
DAD1, ELOB, FKBP1A, MYL12B, POLR2L, PPIB, RABAC1, SPCS1 +2 moreView in SCUBA
Gamma-delta T cellsATP Synthase Complex
Mitochondrial & OxPhos
ATP5F1D, ATP5F1E, ATP5MC2, ATP5MC3, ATP5MF, ATP5MG, ATP5MK, ATP5PD +23 more
Goblet cellsGoblet Secretory Identity
Mucus production & secretion
CREB3L1, ENTPD8, FKBP11, GNE, ITLN1, NPDC1, REP15, SH3BGRL3 +4 moreView in SCUBA
Innate lymphoid cellsRNA Splicing Processing
RNA processing & translation
ATP5F1C, CHMP2A, CHMP4A, CYBA, DSTN, DYNC1I2, DYNLRB1, FKBP3 +16 moreView in SCUBA
Lymphatic endothelialHousekeeping Mixed
Housekeeping
GUK1, LAMTOR4, NDUFB11, NEDD8, PRDX5, RNASEH2C, VPS28, ZNHIT1View in SCUBA
MacrophagesER Protein Glycosylation
Vesicular traficking
AK2, ALG3, ALG5, BABAM1, CKLF, CRELD2, DDOST, DPM3 +21 moreView in SCUBA
Natural Killer cellsCellular Homeostasis
Metabolism
APRT, ATP5F1E, ATP6V0E1, CD63, DYNLRB1, OAZ1, PSMA7, TMSB4X +1 moreView in SCUBA
PericytesER Chaperone UPR
Stress
CALR, HSBP1, HSP90B1, PDIA3, PDIA6, PSMB5, RAB13View in SCUBA
Smooth muscle cellsActivated Myofibroblast
Activation
CNN3, EPHX1, IFI16, IGFBP4, LAPTM4B, NNMT, SERPING1, SULF1 +3 moreView in SCUBA

About the gene

SynonymsTRAPD
ChromosomeX: 153793516-153798499
Predicted locationMembrane
Essential geneNo
Protein classDisease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins

Function

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.