OCIAD1 — OCIA domain containing 1
OCIAD1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
OCIAD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ER-Golgi Trafficking Vesicular traficking | ANXA5, ARF1, ATP6AP2, MORF4L1, MTDH, PTGES3, RAB2A, SELENOF +6 more | View in SCUBA |
| Gamma-delta T cells | Metabolic Housekeeping Housekeeping | ACAP1, ANTKMT, ATP6V0E2, B3GAT3, CCDC57, CHN2, CMTM3, DCTD +12 more | |
| Innate lymphoid cells | RNA Chromatin Regulation RNA processing & translation | ACADM, AURKAIP1, BUD23, CBX3, CMC2, COPB1, DNAJA2, DYNC1LI1 +19 more | View in SCUBA |
| Lymphatic endothelial | Metabolic Housekeeping Housekeeping | CAPNS1, CYB5R3, DMAC1, DUT, EID1, ESD, GNAI2, ISCU +5 more | View in SCUBA |
| Macrophages | ER Protein Processing Housekeeping | ACTR1A, ANXA7, ATP6AP1, ATP6AP2, ATP6V0B, ATP6V0E1, AUP1, BCAP31 +41 more | View in SCUBA |
About the gene
| Synonyms | Asrij, FLJ20455, OCIA, TPA018 |
|---|---|
| Chromosome | 4: 48805212-48861817 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.