PLCL2 — Phospholipase C like 2
PLCL2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLCL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Venous EC Identity Endothelial cell development | CA4, CABP1, CD36, FABP5, FMNL2, IGFBP6, ISLR, LNX1 +6 more | View in SCUBA |
| Enterocytes | Translational repression RNA processing & translation | B3GALT5, CDHR1, EEF2K, FAM13A, PDCD4, PROM1, PTPRJ | View in SCUBA |
| Gamma-delta T cells | T Cell Migration migration & adhesion | BCL2, BPNT2, CCDC88B, DNM2, EDC4, GMDS, LRRC58, MARK3 +14 more | |
| Macrophages | Endosomal Rab Trafficking Vesicular traficking | ABL1, ANKS1A, ARB2A, CAMK1D, CPEB3, DENND4C, DISC1, FBXL17 +15 more | View in SCUBA |
| Mucosal-associated invariant T cell | Calcineurin-NFAT Signaling TCR Signaling | AKT3, CDC14A, IQGAP2, NCALD, NEK7, PLCB1, PPP2R2B, PPP3CA +3 more | |
| Neutrophils | Neutrophil Differentiation Developmental | DACH1, DGKD, FAR1, MPP7, MSRA, PAM, PTBP2, RELL1 +1 more |
About the gene
| Synonyms | KIAA1092, PLCE2 |
|---|---|
| Chromosome | 3: 16802651-17090604 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Transducer |
Function
May play an role in the regulation of Ins(1,4,5)P3 around the endoplasmic reticulum
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.