RASSF2 — Ras association domain family member 2
RASSF2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RASSF2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B-cell activation B cell maturation | ADAM19, ARHGAP30, CD164, CD19, CD47, CLN8, CPEB4, ELK3 +15 more | View in SCUBA |
| CD4⁺ T cells | TGF-beta response Intercellular communication | CLU, COA1, ELK4, GLUL, GPR18, HDGFL3, ORAI2, RAB27B +3 more | View in SCUBA |
| Endothelial | CXCL12 Angiogenic Chemotaxis Chemotaxis | ACKR3, AFAP1L1, ARHGAP18, ARHGEF7, CHST1, CXCR4, FHL3, FSCN1 +15 more | View in SCUBA |
| Hematopoietic progenitor cells | T/NK Cell Identity Lymphcyte development | ATM, BAZ2B, CD53, LCP1, LGMN, MED13L, NKG7, PREX1 +3 more | |
| Mucosal-associated invariant T cell | Cytoskeletal Organization Cytoskeletal | ARAP2, CHD8, CTNNB1, DYNC1H1, EP400, NFATC2, RNF4, SRPRA +4 more |
About the gene
| Synonyms | CENP-34, KIAA0168 |
|---|---|
| Chromosome | 20: 4780023-4823608 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cell cycle |
Function
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.