SCUBA

SIPA1L2 — Signal induced proliferation associated 1 like 2

SIPA1L2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SIPA1L2's module in each cell type

Cell typeModuleShares the module with
EnterocytesSpectrin-actin scaffold
Cytoskeletal
ADD3, DEPTOR, DNAAF9, FYB2, MBOAT2, PRKCB, SETBP1, SNTB1 +2 moreView in SCUBA
Glial cellsGlial Homeostatic Identity
Development
GAS7, NUCKS1, QKI, SEMA3C, SORCS1, TMEM245, VCL, ZBTB20View in SCUBA
Goblet cellsNotch Secretory Specification
Epithelial development
EDN1, EREG, FKBP1A, GPRC5C, HES4, HES5, MYC, NOTCH2 +4 moreView in SCUBA
MacrophagesRho GTPase Signaling
Cytoskeletal
ABCC1, ABR, ANKRD17, ARFGEF2, ARHGAP10, ARID2, ATAD2B, ATP9B +44 moreView in SCUBA
NeutrophilsGranulopoiesis Transcriptional
Developmental
EXT1, KLHL2, MAML3, PDE3B, PHF21A, STAT5B, TPST1
Smooth muscle cellsBMP/TGF-beta response
Activation
APBB2, GLS, ID1, ID2, IRS2, KLF10, RND3, SEC11C +1 moreView in SCUBA

About the gene

SynonymsKIAA1389, SPAR2
Chromosome1: 232397965-232630571
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins
Molecular functionGTPase activation

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.