SELENOF — Selenoprotein F
SELENOF belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SELENOF's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Chaperone Proteostasis Protein processing & ER | BANF1, CCT3, CCT4, CCT5, FXR1, HNRNPH3, HSPB1, MAGOH +7 more | View in SCUBA |
| Fibroblasts | ER-Golgi Trafficking Vesicular traficking | ANXA5, ARF1, ATP6AP2, MORF4L1, MTDH, OCIAD1, PTGES3, RAB2A +6 more | View in SCUBA |
| Gamma-delta T cells | T-bet Effector Differentiation T cell maturation | ABHD17A, BCL7C, CAPNS1, CHST12, DGKZ, EFHD2, FMNL1, GNAI2 +15 more | |
| Innate lymphoid cells | Glycolysis & OxPhos Metabolism | ARPC4, ATP6V1F, BRK1, ENO1, FKBP1A, GAPDH, NEDD8, PYURF +2 more | View in SCUBA |
| Macrophages | ER Protein Processing Housekeeping | ACTR1A, ANXA7, ATP6AP1, ATP6AP2, ATP6V0B, ATP6V0E1, AUP1, BCAP31 +41 more | View in SCUBA |
About the gene
| Synonyms | SEP15 |
|---|---|
| Chromosome | 1: 86862445-86914424 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
May be involved in redox reactions associated with the formation of disulfide bonds (By similarity). May contribute to the quality control of protein folding in the endoplasmic reticulum. May regulate protein folding by enhancing the catalytic activity of UGGT1/UGCGL1 and UGGT2/UGCGL2
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.