SSR1 — Signal sequence receptor subunit 1
SSR1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SSR1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Butyrophilin gd Activation TCR Signaling | ABI1, ADD3, ANXA6, ARHGAP1, ARHGAP25, ARHGAP30, ARHGEF2, BTN3A1 +16 more | |
| Goblet cells | ER Protein Translocation Protein processing & ER | DNAJC3, LMAN1, PDIA6, RPN2, SPCS2, SPCS3, TMED10, TMED2 | View in SCUBA |
| Macrophages | ER Stress UPR Stress | ANKRD9, APEH, ARMCX6, BET1L, CALR, CCDC107, COPS2, DNAJB11 +20 more | View in SCUBA |
| Mucosal-associated invariant T cell | Vesicle Membrane Trafficking Housekeeping | ACSL5, AP2B1, APOBR, CAPRIN1, CAPZA1, DDX23, G3BP1, IARS1 +6 more |
About the gene
| Synonyms | TRAPA |
|---|---|
| Chromosome | 6: 7268306-7347446 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Transporters |
Function
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.