SYTL3 — Synaptotagmin like 3

SYTL3 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SYTL3's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	Chemokine Migration migration & adhesion	CCR6, CYTIP, DDX24, FRMD4B, G3BP2, GNG2, GPBP1, KMT2E +7 more	View in SCUBA
Gamma-delta T cells	TCR Inhibitory Signaling Exhaustion	AFF4, CBLB, CCNH, CCNT1, CHD2, CRYBG1, FYN, ISG20 +9 more
Innate lymphoid cells	Inflammasome Activation Inflammation	ANKRD28, AP3D1, ARHGEF7, CCNH, CD55, CDC42SE1, CHD7, CHKA +19 more	View in SCUBA
Macrophages	PI3K Lipid Signaling Innate immunity	AGPAT4, AREG, DHX34, DNMBP, EEPD1, HIP1, IP6K1, IRAK2 +23 more	View in SCUBA
Monocytes	G-protein Membrane Remodeling Migration & adhesion	ADA, ANKRD9, CXCL16, DNMBP, EPB41L3, GFOD1, GNA12, GNA13 +7 more	View in SCUBA
Mucosal-associated invariant T cell	MAIT Cell Identity T cell maturation	AFF3, DDX3Y, DKK3, DSE, EPAS1, FKBP5, FYN, GLIPR1 +16 more
Natural Killer cells	NK Cytotoxic Signaling Cytotoxicity	BCL2L11, CBLB, CRYBG1, DAZAP2, FYN, GPATCH8, HNRNPUL1, MAPK1 +3 more	View in SCUBA
Neutrophils	TLR2 Innate Signaling Innate immunity	AATK, CHST15, CYRIA, DHX34, ECE1, ERGIC1, MAP4K4, MKNK1 +4 more

About the gene

Synonyms	exophilin-6, SLP3
Chromosome	6: 158650014-158764876
Predicted location	Intracellular
Essential gene	No
Protein class	Predicted intracellular proteins

Function

May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.