TMBIM1 — Transmembrane BAX inhibitor motif containing 1
TMBIM1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMBIM1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Inflammatory hypoxic response Stress | CAPN2, ISG20, LRP10, MUC13, MXD1, TM4SF20, VEGFA | View in SCUBA |
| Gamma-delta T cells | Effector Cell Migration migration & adhesion | ADAM15, ADAM8, ANXA2, APOBEC3G, CD52, CTSC, DSTN, FUT11 +17 more | |
| Macrophages | ER-Lysosome Trafficking Vesicular traficking | BPNT2, CALU, CLPTM1L, CTSB, DHRS7, EMC10, GBA1, GNS +21 more | View in SCUBA |
| Natural Killer cells | KIR+ NK Maturation Immune regulation | AXIN1, ENC1, FAM53B, GTF3C1, KIR2DL1, KIR2DL3, KIR3DL1, KIR3DL2 +3 more | View in SCUBA |
About the gene
| Synonyms | LFG3, PP1201, RECS1 |
|---|---|
| Chromosome | 2: 218274197-218292586 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.