SCUBA

PPDPF — Pancreatic progenitor cell differentiation and proliferation factor

PPDPF belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PPDPF's module in each cell type

Cell typeModuleShares the module with
CD8⁺ T cellsRNA Splicing & ER
RNA processing & translation
ARHGDIB, FKBP8, HNRNPA1, MIF, PFN1, PPP1R18, SNRPD2, TMED2 +2 moreView in SCUBA
EndothelialInflammatory Stress Response
Inflammation
ADI1, APLN, ARL6IP1, ARL6IP4, CCDC88A, DAP, GPR68, HEBP2 +11 moreView in SCUBA
EnterocytesMature colonocyte absorptive
Absorption
ADI1, BRI3, BTG1, CAMK2N1, CTSZ, FXYD3, GUCA2A, GUCA2B +9 moreView in SCUBA
Glial cellsAntioxidant Stress Response
Stress
AP2S1, CSTB, DYNLRB1, HSBP1, MAGED2, NDUFB11, PLPP1, SELENOW +1 moreView in SCUBA
Goblet cellsEpithelial Maturation
Epithelial development
AMN, BAG1, CDC42EP5, CST3, KRT10, NTRK2, NXPE4, PHGR1 +2 moreView in SCUBA
Innate lymphoid cellsmRNA Translation
RNA processing & translation
ABHD14B, ARHGDIA, CD2BP2, EEF2, EIF3L, GYPC, H2AJ, HNRNPA0 +6 moreView in SCUBA
Lymphatic endothelialOxidative Phosphorylation
Mitochondrial & OxPhos
ATP5F1D, ATP5F1E, ATP5MC2, ATP5ME, ATP5MG, COMMD6, COX7C, EIF3K +3 moreView in SCUBA
MacrophagesOxidative Metabolic Program
Mitochondrial & OxPhos
ACADM, CA2, CALM3, CAPG, COQ2, CSRP1, CSTB, DENND2D +29 moreView in SCUBA
Natural Killer cellsResident NK cells
Gut residency
ANXA11, APBB1IP, CD151, CXXC5, HMOX2, LSP1, MPG, SH3BP1 +4 moreView in SCUBA
Smooth muscle cellsCalcium Handling Contractile
Contractility
CALM2, COX7A2, EIF4A2, HSPB1, PLN, UQCRB, YBX1View in SCUBA

About the gene

SynonymsC20orf149, dJ697K14.9, exdpf
Chromosome20: 63520765-63522206
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Molecular functionDevelopmental protein
Biological processDifferentiation

Function

Probable regulator of exocrine pancreas development

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.