SCUBA

NDUFB11 — NADH:ubiquinone oxidoreductase subunit B11

NDUFB11 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFB11's module in each cell type

Cell typeModuleShares the module with
CD8⁺ T cellsMitochondrial ETC/OxPhos
Mitochondrial & OxPhos
AP2S1, BAX, COX6A1, ERH, HSD17B10, LSM2, MAD2L2, MEA1 +7 moreView in SCUBA
EndothelialRespiratory Chain Complex
Mitochondrial & OxPhos
ATP5MG, CHCHD2, HSBP1, MTCH2, NDUFS8, NDUFV2, SNRPD2, UQCR10View in SCUBA
FibroblastsCullin-RING Ubiquitin Ligase
Housekeeping
ARPC3, LAMTOR5, MRPL51, NDUFA11, NDUFC2, OST4, RBX1, RNF7 +3 moreView in SCUBA
Gamma-delta T cellsTranscriptional Elongation Control
DNA/chromatin regulation
ANP32B, AP2M1, ARF5, AURKAIP1, CCDC124, CUEDC2, CYC1, DCTN3 +19 more
Glial cellsAntioxidant Stress Response
Stress
AP2S1, CSTB, DYNLRB1, HSBP1, MAGED2, PLPP1, PPDPF, SELENOW +1 moreView in SCUBA
Innate lymphoid cellsMitochondrial OxPhos
Mitochondrial & OxPhos
ATP5F1D, CAP1, MRPL51, NOP10, PARK7, POLR2F, PSMB3, VDAC1View in SCUBA
Lymphatic endothelialHousekeeping Mixed
Housekeeping
GUK1, LAMTOR4, NEDD8, PRDX5, RNASEH2C, SSR4, VPS28, ZNHIT1View in SCUBA
MacrophagesProtein Homeostasis Mixed
Housekeeping
ABRACL, ADI1, AP2S1, ATP5F1B, BRK1, CFL1, CHCHD2, CLTA +33 moreView in SCUBA
Mucosal-associated invariant T cellCyclophilin-Mediated Folding
Housekeeping
B2M, BBLN, BCL7C, C12orf75, CFL1, EDF1, EIF3L, ERH +10 more

About the gene

SynonymsESSS, Np15, NP17.3
ChromosomeX: 47142071-47145466
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classDisease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins
Biological processElectron transport, Respiratory chain, Transport

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.