PLEKHG1 — Pleckstrin homology and RhoGEF domain containing G1
PLEKHG1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLEKHG1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B cell identity TFs B cell maturation | AFF3, APLP2, C16orf74, FOXP1, IGHM, RCSD1, TSPAN13, WASHC4 | View in SCUBA |
| Enterocytes | Epithelial polarity cytoskeleton Cytoskeletal | ARHGEF10L, ARID5B, CADPS2, CLMN, DGKH, FAR2, LLGL2, PLEKHA5 +3 more | View in SCUBA |
| Lymphatic endothelial | Rho/Ras GTPase Regulation Cytoskeletal | ASAP1, CADPS2, CDK17, ERC1, ETV6, KIF13A, LDLRAD4, LMBR1 +4 more | View in SCUBA |
| Pericytes | BMP Receptor Signaling Developmental | BMPR2, CRK, LRRC8C, PTPRN2, RBMS2, RPS6KA2, SNAP23, TMEM181 +1 more | View in SCUBA |
About the gene
| Synonyms | ARHGEF41, KIAA1209 |
|---|---|
| Chromosome | 6: 150599883-150843665 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Guanine-nucleotide releasing factor |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.