STX11 — Syntaxin 11
STX11 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
STX11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TNF activation survival Immune regulation | BCL2L1, CD82, CFLAR, CMSS1, EPOP, IL21R, KCNN4, KDM2B +12 more | View in SCUBA |
| Gamma-delta T cells | cAMP Lipid Signaling Immune regulation | ABL1, AKIRIN2, B9D2, CEMIP2, CHPT1, CTDP1, DKK3, GGA2 +15 more | |
| Lymphatic endothelial | DNA Damage Autophagy Stress | CKS2, COQ10B, GADD45A, HBP1, MAP1LC3B, MSX1, NR1D1, PHLDA2 +2 more | View in SCUBA |
| Macrophages | Autophagy Vesicle Trafficking Lysosomal & pahgocytosis | ADNP2, AGO2, AP1G1, ARFGAP3, ATG2A, BANP, CHD1, CHD2 +26 more | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB Survival Signaling Immune regulation | BIRC2, CWC25, GATA3, IL4I1, KPNA2, OAT, OTULIN, PIM2 +4 more | |
| Natural Killer cells | Autophagy-Inflammation Stress Stress | BCL2A1, DDIT3, ICAM1, IFFO2, JMJD6, KLF10, MAP1LC3B, MKNK2 +3 more | View in SCUBA |
About the gene
| Chromosome | 6: 144150487-144191939 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Biological process | Protein transport, Transport |
Function
SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.