CKS2 — CDC28 protein kinase regulatory subunit 2

CKS2 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CKS2's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	mRNA splicing factors RNA processing	CALM1, CALM2, CYCS, EIF4A3, HNRNPA0, HNRNPA2B1, HNRNPAB, MRPS6 +12 more	View in SCUBA
CD4⁺ T cells	Pol II Transcription Regulation DNA/chromatin regulation	ABHD5, BAIAP2, BRD2, CBX4, CDKN1C, CITED2, EHD1, EIF4A1 +28 more	View in SCUBA
CD8⁺ T cells	G1/S Entry Checkpoint Cell cycle	ARHGAP11B, ARL6IP1, BUB3, CALM2, CDKN2C, EMC9, MZT1, PTTG1	View in SCUBA
Gamma-delta T cells	G1/S Entry Cell cycle	CDKN2A, CMC2, H2AZ1, H2AZ2, HMGB2, IFI27L1, KPNA2, MAPK9 +15 more
Goblet cells	Mitotic Spindle Assembly Cell cycle	ARHGAP11A, AURKA, CDKN3, CENPA, CKAP5, FAM83D, KIF14, KNL1 +5 more	View in SCUBA
Innate lymphoid cells	ILC3 Transcriptional Identity Differentiation	ABHD5, AKT1S1, ARF4, ATP1A1, EGR3, GADD45B, HES1, HEXIM1 +12 more	View in SCUBA
Lymphatic endothelial	DNA Damage Autophagy Stress	COQ10B, GADD45A, HBP1, MAP1LC3B, MSX1, NR1D1, PHLDA2, STX11 +2 more	View in SCUBA
Monocytes	NR4A Immediate-Early Inflammatory	ANKRD37, CHMP1B, CYCS, EIF4A3, ETV3, GLA, NR4A1, NR4A2 +4 more	View in SCUBA
Natural Killer cells	S/G2M Cell Cycle Cell cycle	CALM2, CDK2AP2, JPT1, KPNA2, NAP1L1, NASP, PRDX1, TUBA1C	View in SCUBA

About the gene

Chromosome	9: 89311195-89316703
Predicted location	Intracellular
Essential gene	No
Protein class	Cancer-related genes, Predicted intracellular proteins
Biological process	Cell cycle, Cell division

Function

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.