MYO1F — Myosin IF

MYO1F belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

MYO1F's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	Activated B cell B cell maturation	ARHGAP25, ARID3A, CFLAR, DUSP4, ENTPD1, PIK3R5, PLXNC1, PREX1 +6 more	View in SCUBA
CD4⁺ T cells	T cell co-receptors T cell development	AGO4, ARRB2, CAPG, CD200R1, CD40LG, CD96, EMB, FKBP11 +13 more	View in SCUBA
Gamma-delta T cells	TCR Proximal Signaling TCR Signaling	ADGRG5, BIN2, C11orf21, C12orf75, CD300A, FGR, GPSM3, LAT +11 more
Innate lymphoid cells	NK Cytotoxic Regulation Cytotoxicity	ARHGAP30, BIN2, CAPN12, CHD9, CLK1, CTSC, CYB5B, DDX27 +29 more	View in SCUBA
Macrophages	Pre-mRNA Splicing Housekeeping	AAK1, ANKRD12, ANKRD13D, ARGLU1, BRD2, C3orf62, CREBZF, DMTF1 +20 more	View in SCUBA
Mucosal-associated invariant T cell	Mature Effector MAIT T cell maturation	ADD3, ANTKMT, APOBEC3G, CCL5, CXXC5, FHL3, GZMK, ITGA6 +7 more
Natural Killer cells	Cytoskeletal Remodeling Cytoskeleton & motility	ADD3, ARHGAP25, ARHGEF3, C1orf21, CAPN2, CYTH1, DGKZ, DIP2A +4 more	View in SCUBA
Neutrophils	Endosomal Vesicle Trafficking Vesicular traficking	FKBP5, FLOT2, IQGAP1, RGS18, RIPOR2, SMAP2, SORL1

About the gene

Chromosome	19: 8520778-8577577
Predicted location	Intracellular
Essential gene	No
Protein class	Disease related genes, Plasma proteins, Predicted intracellular proteins
Molecular function	Actin-binding, Calmodulin-binding, Motor protein, Myosin

Function

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.