PGAM1 — Phosphoglycerate mutase 1
PGAM1 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PGAM1's module in each cell type
About the gene
| Synonyms | PGAM-B, PGAMA |
|---|---|
| Chromosome | 10: 97426191-97433444 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Candidate cardiovascular disease genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase, Isomerase |
| Biological process | Glycolysis |
Function
Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglyceratea crucial step in glycolysis, by using 2,3- bisphosphoglycerate. Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho- glyceroyl phosphate
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.