NDUFA2 — NADH:ubiquinone oxidoreductase subunit A2

NDUFA2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFA2's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	RNA processing splicing RNA processing	BUD31, DNAJC8, EDF1, EIF2S1, GTF3C6, HPRT1, ILF2, LAMTOR5 +11 more	View in SCUBA
CD8⁺ T cells	Metabolic Housekeeping Housekeeping	COX17, DAZAP1, EIF4E, ILF2, MRPL51, SSNA1, TADA3, TPM4	View in SCUBA
Endothelial	Lysosomal Autophagy Program Stress	ABCD4, AKR1A1, ASPH, CD63, CFI, EBP, GNS, MAP1LC3A +4 more	View in SCUBA
Goblet cells	Electron Transport Chain Mitochondrial & OxPhos	ATP5IF1, ATP5ME, COX5B, DCXR, NDUFA3, NDUFB1, NDUFB10, NDUFB7 +5 more	View in SCUBA
Innate lymphoid cells	Mitochondrial OxPhos Biogenesis Mitochondrial & OxPhos	AP1S1, ATOX1, ATP5ME, ATP5MF, C1QBP, CNIH1, CYC1, ERH +22 more	View in SCUBA
Smooth muscle cells	OXPHOS Complex I Mitochondrial & OxPhos	CLTB, COPS6, ETFB, IAH1, MRPS21, NDUFB10, NDUFC2, OAT +3 more	View in SCUBA

About the gene

Synonyms	B8
Chromosome	5: 140638740-140647771
Predicted location	Intracellular
Essential gene	Yes
Protein class	Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Biological process	Electron transport, Respiratory chain, Transport

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.