SCUBA

NDUFB10 — NADH:ubiquinone oxidoreductase subunit B10

NDUFB10 belongs to a gene co-expression module in 11 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFB10's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsOxidative Phosphorylation
Mitochondrial & OxPhos
ANAPC11, AP2S1, ATP5F1A, ATP5F1C, COPE, COX8A, GAPDH, GNG5 +7 moreView in SCUBA
CD4⁺ T cellsProteostasis OxPhos
Housekeeping
AIP, ARPC1B, ATP6V1F, C4orf48, CHMP2A, IL2RG, NDUFA13, PPP1R7 +6 moreView in SCUBA
EnterocytesRespiratory Chain Subunits
Mitochondrial & OxPhos
ATP5F1D, ATP5ME, CHCHD10, COX5A, NDUFB7, PRDX2View in SCUBA
FibroblastsMitochondrial OxPhos
Mitochondrial & OxPhos
ATP5PF, COX6A1, COX6C, GSTP1, MGST3, NDUFA12, NDUFA8, NDUFB4 +6 moreView in SCUBA
Gamma-delta T cellsGeneral Housekeeping Mixed
Housekeeping
ARPC3, CHCHD5, COPZ1, DRAP1, IDH3G, OSTC, POLR2G, PPP1R7 +4 more
Goblet cellsElectron Transport Chain
Mitochondrial & OxPhos
ATP5IF1, ATP5ME, COX5B, DCXR, NDUFA2, NDUFA3, NDUFB1, NDUFB7 +5 moreView in SCUBA
Innate lymphoid cellsMitochondrial Lysosomal Housekeeping
Mitochondrial & OxPhos
BTF3L4, C14orf119, EMC6, ETFA, IER3IP1, JTB, LAMP1, MRPL14 +7 moreView in SCUBA
Lymphatic endothelialFatty Acid Oxidation
Lipid metabolism
ATRAID, ECH1, ECHS1, ETFB, FCGRT, PEBP1, PRDX2, TMEM14CView in SCUBA
MacrophagesMitochondrial Biogenesis
Mitochondrial & OxPhos
AIMP1, ATP5F1D, ATP5MC1, C1QBP, CCT2, CCT3, CCT7, CHCHD1 +38 moreView in SCUBA
Mucosal-associated invariant T cellMitochondrial Housekeeping
Mitochondrial & OxPhos
ARPC3, DUT, GNB2, GPSM3, LSM2, NAA38, PLEKHJ1, REX1BD +7 more
Smooth muscle cellsOXPHOS Complex I
Mitochondrial & OxPhos
CLTB, COPS6, ETFB, IAH1, MRPS21, NDUFA2, NDUFC2, OAT +3 moreView in SCUBA

About the gene

SynonymsPDSW
Chromosome16: 1959538-1961975
Predicted locationIntracellular
Essential geneYes
Protein classDisease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Biological processElectron transport, Respiratory chain, Transport

Function

Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.