RDX — Radixin
RDX belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RDX's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Membrane Transport Endothelial cell development | AQP1, CDH24, CEBPG, CLIC5, FAP, LSM6, OIT3, OSTF1 +9 more | View in SCUBA |
| Innate lymphoid cells | Innate Stress Signaling Inflammation | C19orf25, DNAJC15, IFI16, KIF5B, KRCC1, MAP2K6, PCMTD1, PLIN2 +7 more | View in SCUBA |
| Lymphatic endothelial | NRF2 Oxidative Stress Stress | B4GALT1, CTTNBP2NL, DDX21, DRAM1, GCH1, HNRNPF, MSN, NFE2L2 +11 more | View in SCUBA |
| Pericytes | Actin-ERM Migration Cytoskeletal | CRIP2, DIAPH1, FKBP1A, FXYD5, ITGA5, MRPL17, MSN, NAA38 | View in SCUBA |
| Smooth muscle cells | Integrin adhesion complex Migration & adhesion | ALDH1B1, ALDH2, DST, FERMT2, ITGA5, KLHL42, METTL7A, NFIX +3 more | View in SCUBA |
About the gene
| Synonyms | DFNB24 |
|---|---|
| Chromosome | 11: 109864295-110296712 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Actin capping, Actin-binding |
Function
Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.