TAMALIN — Trafficking regulator and scaffold protein tamalin
TAMALIN belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TAMALIN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | NF-κB Activation Inflammation | DUSP5, GADD45A, HERPUD1, IL21R, KDM6B, MAFF, NAMPT, NFKB1 +13 more | |
| Innate lymphoid cells | ILC3 identity Differentiation | ABCC1, BCL6, CCND3, CELF2, CHKB, DNAAF2, ENSG00000285976, EREG +31 more | View in SCUBA |
| Macrophages | Anti-inflammatory Response Inflammatory | AMPD2, ARRDC2, BHLHE40, CBX4, CDKN1B, CEBPD, CITED2, DENND3 +31 more | View in SCUBA |
| Mucosal-associated invariant T cell | AP-1/MEF2 Activation T cell maturation | ADNP2, BHLHE40, CDK16, DBF4, ETF1, FOSL2, GADD45A, GPR35 +8 more | |
| Natural Killer cells | TGF-beta Response Immune regulation | ANKRD9, AUTS2, CDK17, GNA13, MTFP1, N4BP3, RAB5IF, RBM38 +2 more | View in SCUBA |
About the gene
| Synonyms | GRASP |
|---|---|
| Chromosome | 12: 52006946-52015889 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.