TMEM14C — Transmembrane protein 14C

TMEM14C belongs to a gene co-expression module in 11 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

TMEM14C's module in each cell type

Cell type	Module	Shares the module with
Endothelial	Oxidative Phosphorylation Mitochondrial & OxPhos	ATP5F1D, ATP5MC2, ATP5PO, COX7C, ERP29, HIGD2A, HINT1, IMPDH2 +10 more	View in SCUBA
Fibroblasts	General Housekeeping Housekeeping	ATP6V0E1, C19orf53, CLTA, EDF1, ERH, NEDD8, PARK7, SEC11A +4 more	View in SCUBA
Gamma-delta T cells	DNA Repair Housekeeping Housekeeping	ANAPC16, CCDC85B, CDIP1, CKLF, COTL1, DNAJC4, ECH1, ERCC1 +10 more
Glial cells	Mitochondrial OxPhos Integrity Mitochondrial & OxPhos	ATP5MC3, ATP5PF, CHCHD2, COX6B1, HINT1, PARK7, RBX1, UBL5	View in SCUBA
Hematopoietic progenitor cells	Erythroid Heme Synthesis Erythropoietic	BLVRB, HBQ1, HES6, MPC2, MPST, REXO2, SMIM10, TMEM14B +2 more
Innate lymphoid cells	Mitochondrial OxPhos Mitochondrial & OxPhos	AKR7A2, ANXA6, AP2M1, ARL6IP4, ARPC1B, ATP5MC2, ATP5PB, BSG +21 more	View in SCUBA
Lymphatic endothelial	Fatty Acid Oxidation Lipid metabolism	ATRAID, ECH1, ECHS1, ETFB, FCGRT, NDUFB10, PEBP1, PRDX2	View in SCUBA
Macrophages	Protein Homeostasis Mixed Housekeeping	ABRACL, ADI1, AP2S1, ATP5F1B, BRK1, CFL1, CHCHD2, CLTA +33 more	View in SCUBA
Monocytes	Biosynthetic Metabolic Activation Housekeeping	AHCY, EEF1B2, IMPDH2, NME1, NPM1, NUCKS1, PABPC4, PEBP1 +4 more	View in SCUBA
Natural Killer cells	NK Cytoskeletal Activation Cytoskeleton & motility	CAPG, CLNK, COTL1, EVL, GPR82, ITM2A, PEBP1, PGK1 +3 more	View in SCUBA
Smooth muscle cells	Mitochondrial Housekeeping Housekeeping	APP, COX7A2L, EIF5B, GABARAPL2, LAMTOR4, NDUFAB1, PGAM1, SPCS2 +2 more	View in SCUBA

About the gene

Synonyms	bA421M1.6, C6orf53, HSPC194, NET26
Chromosome	6: 10722915-10731129
Predicted location	Membrane
Essential gene	No
Protein class	Predicted membrane proteins, Transporters
Biological process	Heme biosynthesis

Function

Required for normal heme biosynthesis

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.