SLC16A3 — Solute carrier family 16 member 3
SLC16A3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC16A3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | MMP-driven Fibroblast Remodeling ECM remodeling | AKR1B1, ANPEP, COL27A1, COL7A1, CTSL, IL7R, INHBA, MME +4 more | View in SCUBA |
| Gamma-delta T cells | IRF4 T-cell Activation T cell maturation | APOA1, APOA4, CD59, FCER1G, FES, FUCA1, GEM, GRAMD2B +14 more | |
| Innate lymphoid cells | Mixed Proteostasis Metabolism Metabolism | ADRM1, ANXA11, ATP6V0B, CISD2, COX17, DNAJC8, DR1, EIF3I +18 more | View in SCUBA |
| Macrophages | Phagocytic Endolysosomal Lysosomal & pahgocytosis | ABHD2, ACTN4, AP3S1, ARF6, ATP6V1B2, CD151, CERS2, CNIH1 +27 more | View in SCUBA |
About the gene
| Synonyms | MCT3, MCT4 |
|---|---|
| Chromosome | 17: 82217934-82261129 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted membrane proteins, Transporters |
| Biological process | Symport, Transport |
Function
Proton-dependent transporter of monocarboxylates such as L- lactate and pyruvate. Plays a predominant role in L-lactate efflux from highly glycolytic cells (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.