SPOCK2 — SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
SPOCK2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SPOCK2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Adhesion/Migration migration & adhesion | ADAM28, ADAMTS6, ARHGAP24, ARHGAP5, CHPT1, CLMN, CMTR2, FCMR +11 more | View in SCUBA |
| CD4⁺ T cells | MAF regulatory program Immune regulation | AKAP13, ARID4B, DTHD1, FYN, IKZF3, ISCU, LIMA1, LIMS1 +12 more | View in SCUBA |
| Gamma-delta T cells | Naive T cell quiescence T cell maturation | ADAP1, ARL4C, BCL9L, BMAL1, CALM1, CAMK1D, CD44, CD5 +10 more | |
| Innate lymphoid cells | IFN-driven ILC1 Activation Inflammation | AFF3, AGPAT5, AKIRIN2, APMAP, ARF6, ARHGEF1, DNAJC1, DYNLT3 +21 more | View in SCUBA |
| Mucosal-associated invariant T cell | Stress Granule Response Stress | BZW1, CRTC2, EZR, G3BP2, HERPUD2, HNRNPUL1, MAP3K8, MAPK1IP1L +3 more | |
| Natural Killer cells | Lymphocyte Trafficking Homing & TEM | BCL6, CTSD, LAPTM5, LITAF, ORAI1, P2RY8, PTPRJ, RNF166 +3 more | View in SCUBA |
About the gene
| Synonyms | KIAA0275, testican-2 |
|---|---|
| Chromosome | 10: 72059034-72089032 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
Function
May participate in diverse steps of neurogenesis. Binds calcium
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.