PRSS23 — Serine protease 23
PRSS23 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRSS23's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Coagulation Protease Signaling Inflammation | CFDP1, F2RL3, FRMD8, HTRA1, ITIH5, ME3, PASK, STT3B +1 more | View in SCUBA |
| Fibroblasts | Stromal Fibroblast Activation ECM remodeling | DDR2, FMOD, HSD11B1, LOXL1, METRNL, PRRX2, TWIST2 | View in SCUBA |
| Gamma-delta T cells | Cytotoxic Effector Program cytotoxicity | ADGRG1, ANXA4, CADM1, CX3CR1, FCGR3A, FGFBP2, FGL2, GNLY +14 more | |
| Glial cells | Reactive Glial Activation Activation | AEBP1, ATP5F1E, EEA1, F2R, FN1, IFI16, POLR2L, PSMA4 | View in SCUBA |
| Mucosal-associated invariant T cell | NK-like Cytotoxic cytotoxicity | AKR1C3, BNC2, CLIC3, CX3CR1, FCGR3A, FGFBP2, GNLY, IGFBP7 +3 more | |
| Natural Killer cells | Cytotoxic NK Maturation Cytotoxicity | ADGRG1, AKR1C3, CXCR2, FCGR3A, FGFBP2, GK5, LGR6, MTSS1 +4 more | View in SCUBA |
| Pericytes | Inflammatory ECM Remodeling ECM remodeling | CASP4, CHSY1, FNDC3B, GMFG, ITPRIPL2, LAMB1, MARCKSL1, NECTIN2 +5 more | View in SCUBA |
About the gene
| Synonyms | SIG13, SPUVE |
|---|---|
| Chromosome | 11: 86791059-86952910 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Hydrolase, Protease, Serine protease |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.