SLK — STE20 like kinase
SLK belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLK's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | T cell co-receptors T cell development | AGO4, ARRB2, CAPG, CD200R1, CD40LG, CD96, EMB, FKBP11 +13 more | View in SCUBA |
| Endothelial | ER-Golgi Trafficking Protein processing & ER | ATL3, DIAPH2, ECE1, EID1, GOLIM4, KTN1, MAGT1, PGK1 +4 more | View in SCUBA |
| Gamma-delta T cells | Chromatin Remodeling Signaling DNA/chromatin regulation | AKAP13, BPTF, CARNMT1, CCDC6, CFLAR, CLASP1, CLASP2, DOCK10 +23 more | |
| Macrophages | Microtubule Organization Cytoskeletal | CAMSAP2, DESI2, FAF2, HERPUD2, KCMF1, LSM14A, MAPK6, NRDC +14 more | View in SCUBA |
| Mucosal-associated invariant T cell | STAT4 T cell Identity T cell maturation | ATF7IP, CAMK4, CBLB, CD96, CELF2, DENND4A, IKZF1, JMJD1C +7 more |
About the gene
| Synonyms | KIAA0204, se20-9, STK2 |
|---|---|
| Chromosome | 10: 103967140-104029233 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
| Biological process | Apoptosis |
Function
Mediates apoptosis and actin stress fiber dissolution
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.