ZSWIM6 — Zinc finger SWIM-type containing 6
ZSWIM6 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZSWIM6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Focal adhesion actin Migration & adhesion | BAZ2B, CARMIL1, COP1, FRYL, KIF13A, LPP, MYO6, PALLD +4 more | View in SCUBA |
| Gamma-delta T cells | Late Activation Autophagy Immune regulation | BCL3, BRD1, CREM, DUSP8, FAM177A1, FBXO33, FOSL2, GABARAPL1 +19 more | |
| Lymphatic endothelial | MAPK-ERK Signaling migration & adhesion | ARIH1, BRAF, CPNE8, DENND4A, ELF2, FBXO11, FNDC3B, GRB10 +6 more | View in SCUBA |
| Macrophages | Ubiquitin Proteasome Regulation Housekeeping | ARIH1, BTAF1, CLASP2, DENND4A, DYRK1A, FBXO11, FBXW7, GATAD2B +8 more | View in SCUBA |
| Monocytes | Macrophage Innate Activation Innate immunity | DMXL2, FGL2, HSD17B4, KCTD12, MPEG1, PTPRC, SAMHD1, TLR4 +1 more | View in SCUBA |
| Mucosal-associated invariant T cell | Epigenetic Chromatin Regulation DNA/chromatin regulation | ASXL1, CREBBP, FNIP1, GATAD2A, PELI1, PNRC1, RAPGEF1, RYBP +1 more | |
| Neutrophils | PI3K Chemotaxis Signaling Chemotaxis | ABCA1, ACSL1, ALDH1A2, CRK, INPP5A, LIMK2, NUP98, PIK3R5 +6 more |
About the gene
| Synonyms | KIAA1577 |
|---|---|
| Chromosome | 5: 61332258-61546172 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Biological process | Neurogenesis |
Function
involved in nervous system development, important for striatal morphology and motor regulation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.