HDLBP — High density lipoprotein binding protein
HDLBP belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HDLBP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | UPR / ER Stress Protein processing & ER | CALR, CANX, CTSB, CTTN, GRN, HSP90B1, HSPA5, HYOU1 +10 more | View in SCUBA |
| Fibroblasts | Collagen ECM Production ECM production | AEBP1, ANGPTL2, ANTXR1, CERCAM, CLTC, COL1A1, COL1A2, COL3A1 +12 more | View in SCUBA |
| Innate lymphoid cells | JAK-STAT Cytokine Signaling Inflammation | AASDHPPT, ARHGAP9, CHURC1, CIDEB, CSK, DCAF7, DENND2D, EDEM2 +23 more | View in SCUBA |
| Macrophages | mRNA Splicing Processing Housekeeping | AP3D1, BAZ1B, CCDC47, CHTOP, CTCF, EIF1AX, EIF3A, HNRNPD +29 more | View in SCUBA |
| Mucosal-associated invariant T cell | Epigenetic Maintenance DNA/chromatin regulation | ATAD2B, ATXN10, DENND6A, DGLUCY, DMTF1, FYCO1, GALK2, HELZ +13 more |
About the gene
| Synonyms | HBP, VGL |
|---|---|
| Chromosome | 2: 241227264-241317061 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport |
Function
Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.