S100A16 — S100 calcium binding protein A16
S100A16 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
S100A16's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Mitochondrial Oxidative Stress Stress | AGTRAP, AP2M1, ECHS1, ECSCR, EDF1, EIF5A, NEDD8, PARK7 +5 more | View in SCUBA |
| Fibroblasts | Proteolytic Fibroblast State ECM remodeling | ANXA2, CTSK, EMP3, LGALS3, MPZL1, PCOLCE, ROBO1, S100A10 +3 more | View in SCUBA |
| Glial cells | Proteostasis Stress Response Stress | ATOX1, ATP5MG, ATP6V0E1, C19orf53, C4orf3, COX7B, CYSTM1, GUK1 +7 more | View in SCUBA |
| Goblet cells | S100 Calcium Signaling Stress | CIB1, CLDN7, CLTB, GUK1, MYL12B, MYL6, RHOC, S100A11 +4 more | View in SCUBA |
| Smooth muscle cells | Pericellular Proteolysis ECM remodeling | AHNAK2, BNC2, CRYBG3, CTSA, HTRA1, MMP14, SNX9, TMED10 | View in SCUBA |
About the gene
| Synonyms | DT1P1A7, MGC17528, S100F |
|---|---|
| Chromosome | 1: 153606886-153613145 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transporters |
Function
Calcium-binding protein. Binds one calcium ion per monomer. Can promote differentiation of adipocytes (in vitro) (By similarity). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.