TSPAN2 — Tetraspanin 2
TSPAN2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TSPAN2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Arterial EC Identity Endothelial cell development | AFAP1L2, BMP4, CFAP36, FUT8, ITPR2, JAG1, LTBP4, NEBL +6 more | View in SCUBA |
| Gamma-delta T cells | Tissue-resident gd T Tissue residence | AKR1C3, ASCL2, BFSP1, CARNS1, CD320, CES1, CMKLR1, CTBP2 +21 more | |
| Hematopoietic progenitor cells | Cytoskeletal Remodeling Cytoskeletal | AHNAK, ANXA1, ATP2B1, DPYSL3, FHL1, IDS, MBOAT7, MTURN +5 more | |
| Monocytes | Classical Monocyte Trafficking Migration & adhesion | ANXA6, CKAP4, EMB, F5, GCA, MAP2K6, MPP7, MSRB1 +4 more | View in SCUBA |
| Pericytes | Arterial Pericyte Identity Developmental | ATP13A3, BMX, FBLN2, GJA5, KCTD12, LTC4S, PLLP, SEMA3G +1 more | View in SCUBA |
| Smooth muscle cells | Mesenchymal Adhesion Program Migration & adhesion | ANTXR1, BAG2, CDH11, COL12A1, CTSB, FHL3, FSTL3, HEPH +6 more | View in SCUBA |
About the gene
| Synonyms | FLJ12082, TSN2, TSPAN-2 |
|---|---|
| Chromosome | 1: 115048011-115089503 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.