SCUBA

NKTR — Natural killer cell triggering receptor

NKTR belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NKTR's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsChromatin & genome maintenance
DNA/chromatin regulation
ARID1B, ASH1L, ATM, ATRX, BOD1L1, DDX17, KANSL1, MARF1 +8 moreView in SCUBA
CD4⁺ T cellsPost-transcriptional regulation
RNA processing
BCL11B, CCDC14, CHD2, CHD6, CREBZF, DDX39B, DNASE1, EVI2B +21 moreView in SCUBA
Gamma-delta T cellsCentrosome Organization
DNA/chromatin regulation
AKAP9, ARMCX6, CCNT2, CEP350, CUL5, DDHD1, DDX42, DENND6A +23 more
Innate lymphoid cellsNK Cytotoxic Regulation
Cytotoxicity
ARHGAP30, BIN2, CAPN12, CHD9, CLK1, CTSC, CYB5B, DDX27 +29 moreView in SCUBA
Lymphatic endothelialPre-mRNA Splicing
RNA processing & translation
ARGLU1, ATRX, BPTF, DDX17, DST, LUC7L3, N4BP2L2, PNISR +6 moreView in SCUBA
MacrophagesPre-mRNA Splicing
Housekeeping
AAK1, ANKRD12, ANKRD13D, ARGLU1, BRD2, C3orf62, CREBZF, DMTF1 +20 moreView in SCUBA
Mucosal-associated invariant T cellCircadian Transcriptional Regulation
DNA/chromatin regulation
ABCB1, ANKRD12, ATOSA, BMAL1, CEP250, GCC2, MIA3, MIER1 +2 more
NeutrophilsmRNA Splicing Processing
Housekeeping
ABCA13, ATP2A3, EMB, FBXO9, LUC7L3, OGT, PAXBP1, PNN +8 more

About the gene

Synonymsp104
Chromosome3: 42600655-42648735
Predicted locationIntracellular
Essential geneNo
Protein classEnzymes, Metabolic proteins, Predicted intracellular proteins
Molecular functionIsomerase, Rotamase

Function

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Component of a putative tumor-recognition complex involved in the function of NK cells

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.